System.Speech.dll object not getting set to an instance of

I talked to GoDaddy customer care support they told me System.Speech.dll will not work on shared hosting.

Do you know the alternative text to speech library?

should be in OS folder, for example in my system it is there at C:\Windows\WinSxS,  if not there you can download and follow registering instructions

https://www.nuget.org/packages/System.Speech.dll/ 

What user account is the code running under when executed from ASP.NET? If the Speech API is touching the registry like the call stack suggests, it possibly has different permissions than the account you used to run the code manually.

If you can't just make the application pool for your site run with the same account you log into the machine with, I've had some success using Process Monitor https://docs.microsoft.com/en-us/sysinternals/downloads/procmon to track down this kind of problem before. Basically, execute the code that fails while Process Monitor is running and look for 'ACCESS DENIED' in the 'Result' column (or anything else that looks suspicious). Quickly switching the application pool to use your standard user account will be the fastest way to rule out security or permission related problems though.